I-47: ART Outcome in PCOS Patients

PCOS is still a problem in gynecology and infertility. Especially in ART the problem of PCOS patients is bigger and more highlighted. These patients are prone to over and under stimulation. Strategies to overcome hyper stimulation are: use of metformin, ovarian drilling, use of minimal stimulation, suppressing LH with use of OCP or GnRh analogues, use of GnRh antagonist in COH. But none of these strategies are complotely accepted and there are still questions about their efficacy. To overcome the problem of under stimulation, there are more difficulties. Solution like step up gonadotropin protocols, use of GnRh antagonist instead of agonist, use of minimal stimulation is still under debate. Other problem in ART of PCOS patients is the high rate of empty follicle syndrome, the higher proportion of eggs in Germimal vesicle or metaphase stage. In the detail of lecture we unill go through all these.